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匹配条件: “Medhi Bikash” ,找到相关结果约350条。
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Efficacy of Fexofenadine in the Indian Population suffering from Alergic Rhinitis & Chronic Urticaria
Bikash Medhi
JK Science : Journal of Medical Education & Research , 2006,
Abstract: The present study was designed to evaluate the efficacy of fexofenadine in the Indian population sufferingfrom allergic rhinitis and chronic urticaria. A total number of two hundred patients of either sex withsimilar demographic profile were included in the study according to inclusion and exclusion criteria.These patients were treated with fexofenadine 120mg once daily for allergic rhinitis and fexofenadine180mg for chronic urticaria for 7 days. The efficacy was evaluated on the basis of symptoms evaluationscale score and medication effectiveness scale score at baseline, on the 3rd day and on the 7th day ofcompletion of treatment. Results indicate that fexofenadine is highly effective in the Indian population(p<0.001) suffering from allergic rhinitis and chronic urticaria.
Effect of esomeprazole on the pharmacokinetics of carbamazepine
Medhi Bikash,Singh Pawan,Prakash Ajay,Avti Pramod
Indian Journal of Pharmacology , 2011,
Abstract: Objective : Present study was carried out to evaluate effect of esomeprazole on the pharmacokinetics of carbamazepine in rabbits. Materials and Methods : Study was conducted at Department of Pharmacology, Postgraduate Institute of Medical Education and Research from March to October 2007. In a parallel design study, carbamazepine 40 mg/kg/day was given orally for 14 days. On day 15, blood samples were taken at various time intervals between 0 and 24 hours. In esomeprazole group, carbamazepine was administered for 14 days as above. On day 8, esomeprazole 2.8 mg/kg/day along with carbamazepine 40 mg/kg/day was administered till 14 days and blood samples were drawn on 15 th day. Plasma levels of carbamazepine were assayed by high-performance liquid chromatography and pharmacokinetic parameters were calculated. Results : In all groups there was a decrease in the AUC 0-24 when carbamazepine was coadministered with esomeprazole. The decrease in AUC 0-24 (22.78 ± 4.71 to 10.46 ± 2.29), C max (2.76 ± 0.77 to 1.412±1.08), T max (2.83 ± 0.17 to 3 ± 0.40) was statistically significant (P < 0.05) when esomeprazole was given along with carbamazepine. Additionally, absorption and elimination constant were also altered significantly. Conclusions : These results suggest that concomitant use of esomeprazole alters the pharmacokinetics of carbamazepine. Confirmation of these results in human studies will warrant changes in carbamazepine dose or frequency when esomeprazole is coadministered.
Scrub Typhus: Clinical Approach
Punit Dhamija, Dipika Bansal, Deonis Xess, Bikash Medhi
JK Science : Journal of Medical Education & Research , 2010,
Abstract: Not Available
Sodium glucose co-transporter 2 inhibitors for glycemic control in type 2 diabetes mellitus: Quality of reporting of randomized controlled trials
Bikash Medhi,Harish Kumar,Niti Mittal,Rakesh Mittal
- , 2016, DOI: 10.4103/2229-3485.173777
Abstract: Sodium glucose co-transporter 2 inhibitors represent a novel class of antidiabetic drugs. The reporting quality of the trials evaluating the efficacy of these agents for glycemic control in type 2 diabetes mellitus has not been explored. Our aim was to assess the reporting quality of such randomized controlled trials (RCTs) and to identify the predictors of reporting quality
Drug safety alerts of pharmacovigilance programme of India: A scope for targeted spontaneous reporting in India
Anusha Thota,Bikash Medhi,Gyanendra Nath Singh,Pramod Kumar,Prasad Thota,Shabir Sidhu,V. Kalai Selvan
- , 2018, DOI: 10.4103/picr.PICR_29_17
Abstract: The National Coordination Centre-Pharmacovigilance Programme of India (NCC-PvPI), Indian Pharmacopoeia Commission works under the aegis of Ministry of Health and Family Welfare, Government of India. It promotes patient safety in India and also supports postmarketing surveillance programs. Currently, almost hundred thousand case reports are submitted to NCC-PvPI each year through its 250 ADR Monitoring Centers (AMCs) located across India, and India is the one of the top ten contributor countries under WHO-Uppsala Monitoring Centre since 2012 and start issuing drug safety alerts from March 2016
Effects of Growing Conditions of Marigold in Ilam District, Nepal  [PDF]
Bikash Khanal
American Journal of Plant Sciences (AJPS) , 2014, DOI: 10.4236/ajps.2014.522354
Abstract:

Different growing conditions with temperature and sunlight variation could vary in flower growth and quality of marigold. Plant growth and flowering characteristics are compared in three different conditions viz. plastic house, shade house and open field. Three varieties of marigold viz. Marvel Yellow, Marvel Orange and Marvel Garland with similar cultural practices were grown and observed. Each variety with 6 replications was grown in three different growing conditions. Plant height, leaves formation, length of leaves, number of days to flower, number of flowers per plant and post harvest analysis were recorded. Plant growth characteristics followed by flowering behavior were found significantly better in plants grown under plastic house. During post harvest experiment Marvel Garland variety grown under plastic house with wet post harvest treatment was found significantly better compared to other conditions.

Modernism in Baghdad
Medhi, Suad.
DC PAPERS : Revista de Crítica y Teoría de la Arquitectura , 2008,
Abstract:
Synthesis, characterization and photophysical properties of quinolin-8-olato chelated osmium(II) organometallics bearing a pendant imine-phenol motif and electrogeneration of trivalent analogue  [PDF]
Bikash Kumar Panda
Open Journal of Inorganic Chemistry (OJIC) , 2012, DOI: 10.4236/ojic.2012.23008
Abstract: The reaction of Os(RL1)(PPh3)2(CO)Br, 1b, with qui-nolin-8-ol (HQ), 2, has furnished complexes of the type [Os(RL2)(PPh3)2(CO)(Q)], 3, in excellent yield (RL1 is C6H2O-2-CHNHC6H4R(p)-3-Me-5, RL2 is C6H2OH-2-CHNC6H4R(p)-3-Me-5 and R is Me, OMe, Cl). In this process, quinolin-8-olato (Q) undergoes five-membered chelation, the iminium-phenolato function tautomerizing to the imine-phenol function. The trans geometry of the Os(PPh3)2 fragment is consistent with the occurrence of a single 31P resonance near –6.0 ppm in 3. In dichloromethane solution, 3 displays a quasireversible 3+/3 couple near 0.40 V vs. SCE (3+ is the osmium (III) analogue of 3). Coulometrically generated solutions of 3+ displays a strong absorption near 340 nm, 415 nm and 500 nm and are one-electron paramagnetic (low-spin d5, S = 1/2) and show rhombic EPR spectra in 1:1 dichloromethanetoluene solution at 77 K with g values near 2.44, 2.20, 1.83. Distortion parameters using the observed g values have been computed. Solutions of 3 absorb near 420 nm and emit near 510 nm at 298 K and 580 nm at 77 K. The fluorescence is believed to originate from the 3MLCT state.
Multigrid One-Shot Method for PDE-Constrained Optimization Problems  [PDF]
Subhendu Bikash Hazra
Applied Mathematics (AM) , 2012, DOI: 10.4236/am.2012.330216
Abstract: This paper presents a numerical method for PDE-constrained optimization problems. These problems arise in many fields of science and engineering including those dealing with real applications. The physical problem is modeled by partial differential equations (PDEs) and involve optimization of some quantity. The PDEs are in most cases nonlinear and solved using numerical methods. Since such numerical solutions are being used routinely, the recent trend has been to develop numerical methods and algorithms so that the optimization problems can be solved numerically as well using the same PDE-solver. We present here one such numerical method which is based on simultaneous pseudo-time stepping. The efficiency of the method is increased with the help of a multigrid strategy. Application example is included for an aerodynamic shape optimization problem.
Antioxidant Capacity and Phenolic Content of Some Nepalese Medicinal Plants  [PDF]
Bijaya Laxmi Maharjan, Bikash Baral
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.48200
Abstract:

Antioxidant capacities and phenolic contents of medicinal plants namely Usnea longifolia, Cetraria nepalensis, Parmelia minarum, Everniastrum nepalense, Rhododendron anthopogon and Fritillaria delavayi were analyzed via Folin-Ciocaltau assay, Ferric reducing activity power assay and 2,2-Diphenyl-1-picrylhydrazyl assay. All the tested plants depicted the antioxidant activity with variation in extent of activity among the plants. The FRAP (F-value: 387.4), DPPH (F-value: 89.684) and TPC (F-value: 559.163) values between the extracts showed the highly significant differences (P < 0.01). This study indicated the strong antioxidant potential of R. anthopogon among the plants tested.

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